Name | Diisobutylaluminum hydride |
Synonyms | DIBAL-H DIBAH~DIBAL-H Diisobutylaluminum hydride Di-i-butylaluminum hydride Diisobutylaluminium hydride hydrido[bis(2-methylpropyl)]aluminum bis(2-methylpropyl)aluminum(1+) hydride Diibutylaluminumhydrideinhexanecolorlessliq DiisobutylaluMinuM hydride solution 1.0 M in cyclohexane |
CAS | 1191-15-7 |
EINECS | 214-729-9 |
InChI | InChI=1/2C4H9.Al.H/c2*1-4(2)3;/h2*4H,1H2,2-3H3;/q;+1;-1/rC8H18Al.H/c1-7(2)5-9-6-8(3)4;/h7-8H,5-6H2,1-4H3;/q+1;-1 |
Molecular Formula | C8H19Al |
Molar Mass | 142.218 |
Density | 1.23 g/mL at 25 °C |
Melting Point | -70℃ |
Boling Point | 65 °C |
Flash Point | 40 °F |
Water Solubility | vigorous reaction |
Physical and Chemical Properties | Diisobutyl aluminum hydride is also called Dibal. Colorless liquid. Relative molecular mass 122.22. Relative density 0.789 (25 ℃). Melting point -47 ℃. Boiling point 140 ℃(0.533 × 103Pa). The viscosity 18.0mpa s(25 ℃). It reacts violently in water to produce hydrogen and isobutane. Tetrahydrofuran is not suitable as a Dibal solvent because the two react to form coordination compounds. |
Use | 二异丁基氢化铝是有机合成中有用的还原剂。使用它的一些还原方法包括将酯转化为醛,以及将无环酯还原乙酰化为α-乙酰氧基醚。它被用于连续减少流量,以合成甲磺酸埃里布林(一种抗癌药)的偶联反应合成。 |
Hazard Symbols | F - Flammable C - Corrosive |
Risk Codes | R11 - Highly Flammable R35 - Causes severe burns R63 - Possible risk of harm to the unborn child R65 - Harmful: May cause lung damage if swallowed R67 - Vapors may cause drowsiness and dizziness |
Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S29 - Do not empty into drains. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S46 - If swallowed, seek medical advice immediately and show this container or label. S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. |
UN IDs | UN 3394 |